{"id":17473,"date":"2026-08-21T11:26:37","date_gmt":"2026-08-21T10:26:37","guid":{"rendered":"https:\/\/www.chemicalukexpo.com\/?p=17473"},"modified":"2026-08-21T11:26:38","modified_gmt":"2026-08-21T10:26:38","slug":"cn-bio-wins-180000-funding-to-advance-animal-free-pharmacokinetic-testing","status":"publish","type":"post","link":"https:\/\/www.chemicalukexpo.com\/cn-bio-wins-180000-funding-to-advance-animal-free-pharmacokinetic-testing\/","title":{"rendered":"CN Bio wins \u00a3180,000 funding to advance animal-free pharmacokinetic testing"},"content":{"rendered":"\t\t
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CN Bio wins \u00a3180,000 funding to advance animal-free pharmacokinetic testing<\/h3>

From LaboratoryNews<\/span><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t
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\"\"CN Bio<\/a><\/span> has been awarded \u00a3180,000 from Innovate UK<\/a> to develop a more human-relevant approach to pharmacokinetic (PK) testing in drug development. The project aims to improve understanding of how potential medicines are absorbed, distributed, processed and cleared by the body, while reducing dependence on animal studies.<\/p>\n

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Working with the <\/a>National Centre for the Replacement, Refinement and Reduction of Animals in Research<\/a><\/span>, CN Bio will combine organ-on-a-chip data with physiologically based pharmacokinetic (PBPK) modelling. This approach is designed to translate laboratory findings into predictions that can be interpreted in a clinical setting.<\/div>\n
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The work builds on CN Bio\u2019s dual-organ Gut\/Liver microphysiological system, which recreates key aspects of human tissue biology. The company will also explore adding a kidney model to assess renal clearance and other processes involved in drug excretion.<\/div>\n
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The initiative supports the UK Government\u2019s target to reduce the use of dogs and non-human primates in dedicated PK studies by 35% by 2030. CN Bio will also investigate automation and work with contract research organisations to help create a standardised, scalable workflow for wider industry adoption.<\/div>\n
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Find out more here<\/a><\/span><\/span><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

CN Bio has received \u00a3180,000 in Innovate UK funding to combine organ-on-a-chip technology with computer-based modelling, creating a more human-relevant alternative to some animal pharmacokinetic studies.<\/p>\n","protected":false},"author":1711,"featured_media":17481,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"none","_seopress_titles_title":"Sasol International Chemicals investment in Brunsb\u00fcttel, Germany","_seopress_titles_desc":"Sasol International Chemicals is investing \u20ac60 million to expand advanced alumina production in Brunsb\u00fcttel, Germany, boosting high\u2011performance capacity and improving efficiency.","_seopress_robots_index":"","footnotes":""},"categories":[40],"tags":[],"edition":[],"class_list":["post-17473","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/posts\/17473","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/users\/1711"}],"replies":[{"embeddable":true,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/comments?post=17473"}],"version-history":[{"count":5,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/posts\/17473\/revisions"}],"predecessor-version":[{"id":17523,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/posts\/17473\/revisions\/17523"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/media\/17481"}],"wp:attachment":[{"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/media?parent=17473"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/categories?post=17473"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/tags?post=17473"},{"taxonomy":"edition","embeddable":true,"href":"https:\/\/www.chemicalukexpo.com\/en\/wp-json\/wp\/v2\/edition?post=17473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}